Hypothyroidism presenting as a fissure tongue.

We are reporting a case of hypothyroidism presenting as fissured tongue, demonstrating significant resolution of fissure tongue upon thyroid hormone replacement therapy.

Soluble LPS receptor CD14 is increased in saliva of patients with geographic tongue.

OBJECTIVES: The soluble bacterial pattern recognition receptor, sCD14 augments inflammatory responses in oral cavity. The aim of the study was to investigate whether patients with geographic tongue (GT) with and without fissured tongue (FT) have impaired inflammatory regulation, manifesting as increased levels of sCD14 in the saliva. MATERIAL AND METHODS: An enzyme-linked immunosorbent assay was used to measure the amount of sCD14 in whole and parotid saliva of patients diagnosed with GT (GT whole, n = 21; GT parotid, n = 23) and control subjects (GT whole, n = 25; GT parotid, n = 18). The levels of sCD14 were also evaluated according to our previous clinical assessment of GT based on the number of lesions detected on the tongue, as 'mild' (a single lesion), 'moderate' (2-5 lesions), or 'severe' (≥6 lesions). Diagnosis of FT was established when multiple grooves or fissures were observed on the dorsal and lateral surfaces of the tongue. RESULTS: GT patients had significantly higher sCD14 levels in whole (p<.05) and parotid saliva (p<.001), compared with controls. GT patients with FT had significantly increased sCD14 levels only in parotid saliva. A gradual increase in sCD14 levels in parotid and unstimulated saliva was seen in GT patients with multiple tongue lesions compared with single lesions. CONCLUSIONS: GT patients had increased sCD14 in both parotid and unstimulated saliva. sCD14 seems to increase local inflammatory responses, which suggests its involvement in the pathophysiology of GT.

Principales hallazgos clinicos en la lengua en una poblacion de Cali / Main findings in the tongue among a Cali population: pilot study

La lengua puede ser un órgano de gran utilidad para el diagnostico temprano de afecciones sistémicas. En este artículo se presentan los principales cuadros patológicos encontrados en la evaluación clínica de la lengua de 400 pacientes provenientes de la consulta de primera vez en el servicio odontológico de la Clínica Santa Rosa de COMFANDI y la consulta particular de los Odontólogos que realizaron la investigación. Los pacientes para ser incluidos en el estudio debían ser mayores de 5 años de edad y firmar su consentimiento informado. Como criterio de exclusión se consideraron pacientes con afecciones psíquicas y afecciones sistémicas agudas. Con referencia a la localización de los cambios identificados, el dorso de la lengua fue la región donde se visualizaron en un 70 % de los pacientes evaluados. Los tipos de lengua mas frecuentemente identificados fueron: lengua saburral en 30% de los pacientes, lengua fisurada en el 11,25 %, lengua geográfica en el 7.8%, glosodinia en el 6.75% y macroglosia secundaria en el 5.8%. Adicionalmente, en la lengua de un mismo individuo, en menor proporción, se encontraron diversas combinaciones de afecciones; la más frecuente, la lengua sabural y fisurada en el 3.5% de los examinados. En general, las tres más frecuentes afecciones de la lengua fueron lesiones de carácter benigno y asintomático como son la lengua saburral, la lengua fisurada y la lengua geográfica. Un porcentaje importante tuvo la glosodinia, que amerita determinar sus causas para poder ofrecer un tratamiento. La macroglosia secundaria fue otra patología encontrada y esta se evitaría con el reemplazo oportuno de los dientes perdidos. A dos de los pacientes con ulceras linguales, se les diagnostico carcinoma escamocelular. En el examen clínico de un paciente que asista a la consulta Odontológica la valoración de la lengua reviste gran utilidad diagnostica y debe ser realizada por todos los profesionales de la Odontología.

The Tongue is an important body organ that can be used to perform early diagnosis of systemic or local medical and oral diseases. In this study the tongue of 400 people coming from COMFANDI – EPS at Santa Rosa Dental Service, and some private dental offices were evaluated in Cali- Colombia. Results are presented as more common tongue pathologic findings. Tongue pathologic diseases were in order of frequency: Saburral tongue (30%), Fissure tongue (11.25%), Geographic tongue (7.8%), Glossy tongue (6.75%), Secondary macro-glosia were the more frequent single diagnosis. However, tongue disease combinations like saburral and fissure tongue (3.5%) were present but less frequent. More common tongue diagnostics were benign and asymptomatic diseases. Other diagnosis such as Secondary macroglosia may be related to molar extractions and could be solved by dental replacement. Regarding life threatening diseases on the tongue, two patients had lingual ulcers that later confirmed to be escamous carcinoma. Thus, tongue careful evaluation during dental first examination is an important procedure to help diagnose and treat benign and malign tongue diseases.